At Sacred Vine, we honor ayahuasca as a sacred sacrament for spiritual growth, healing, and communion with the divine. Participant safety is our highest priority. These guidelines are informed by established entheogenic church practices (including UDV, Santo Daime, and aligned organizations like the Sacred Plant Alliance), medical literature, and harm-reduction best practices.

Our Commitment to Safety

As a dedicated entheogenic church, Sacred Vine follows rigorous screening, preparation, ceremony support, and integration protocols. Ceremonies are led by experienced facilitators in a controlled, supportive environment.

1. Pre-Ceremony Screening (Required for All Participants)

All prospective participants complete a confidential medical and psychological questionnaire. A review process (potentially including consultation with qualified professionals) determines eligibility.

Absolute Contraindications:

• Cardiovascular conditions: Uncontrolled high blood pressure, heart disease, arrhythmias, history of heart attack or stroke.

• Psychiatric history: Schizophrenia, psychosis (personal or strong family history), bipolar disorder with manic episodes.

• Neurological: Epilepsy or seizure disorders.

• Pregnancy, breastfeeding, or planning pregnancy.

• Advanced liver, kidney, or other serious organ disease.

• Recent major surgery or acute illness.

Medication & Substance Interactions (Critical – Must Disclose):

Ayahuasca contains MAO inhibitors. Dangerous interactions can occur. Taper under medical supervision (typically 2–6 weeks prior, depending on the substance):

• Antidepressants (SSRIs, SNRIs, MAOIs, tricyclics).

• Stimulants, ADHD medications, diet pills.

• Antihistamines, decongestants, certain cough medicines (DXM).

• Blood pressure medications, opioids, lithium, etc.

• Recreational substances (alcohol, cocaine, MDMA, cannabis in excess, etc.).

Full list provided during intake. We may require medical clearance. 

 **St. John’s Wort and certain herbs also restricted. 

Important Disclaimer: These guidelines are for informational and educational purposes. They do not constitute medical advice. Ayahuasca is a powerful entheogen. We require full medical disclosure and reserve the right to deny participation for safety reasons. Participation is voluntary and reserved for sincere members of our spiritual community.

Do not stop taking any prescribed medications without consulting your doctor.

Our greatest responsibility is to ensure your health and safety throughout the ceremony and beyond and we require your honest and open communication to make that happen. We will not turn away anyone we can safely bring into the ceremony. Please contact us to learn more.